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The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.
Acquisto del libro
Nongenotoxic Carcinogenesis, A. Cockburn, Lewis L. Smith
- Lingua
- Pubblicato
- 1994
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- Prezzo
- 1,61 €
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- Titolo
- Nongenotoxic Carcinogenesis
- Lingua
- Inglese
- Autori
- A. Cockburn, Lewis L. Smith
- Editore
- Springer
- Pubblicato
- 1994
- Formato
- Copertina rigida
- Pagine
- 240
- ISBN10
- 3540583424
- ISBN13
- 9783540583424
- Serie
- Tag
- Scienza, Medicina, Ricerca, Cancro, tumori, Biochimica, Farmacologia, Prevenzione, Oncologia, Cancro al seno, Ormoni, Ricerca medica, Tossicologia, Trascrizione
- Descrizione
- The majority of human chemical carcinogens are capable of damaging DNA and are loosely defined as "genotoxic." On the other hand some chemicals which are described as non-genotoxic appear to increase the incidence of rodent cancers only as a secondary consequence of other induced toxicity. The primary action does not involve DNA damage. This book presents the concept of non-genotoxic carcinogenesis, including possible mechanisms of action. The papers presented by prominent workers provide a detailed insight into the complexity of the field.