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Series of the Centro de Estudios Científicos: Pumps, Transporters, and Ion Channels

Studies on Their Structure, Function, and Cell Biology

Parametri

  • 182pagine
  • 7 ore di lettura

Maggiori informazioni sul libro

This compilation of articles features talks from the Centro de Estudios Cientificos (CECS) in Valdivia, celebrating the 60th birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre, a prominent figure in channel Biophysics, initially trained as a Biochemist but transitioned to biophysics under the mentorship of Guayo (Eduardo) Rojas during his Ph.D. at the Laboratorio de Fisiologia Celular in Montemar. His influential work at the N.I.H. with Gerald Ehrenstein and Harold Lecar marked a significant milestone in single ion channel Biophysics. This foundational research, conducted in planar bilayers, laid the groundwork for understanding voltage-dependent conductances through single channel studies, predating the later patch clamping techniques. Latorre was among the first to identify the significance of calcium-activated potassium channels and to investigate their properties in detail. He advanced the understanding of voltage and calcium modulation of open probability and conducted thorough studies on gating and its modulation by other ions. Additionally, he explored permeation and selectivity, producing seminal studies on water molecules within channels and barium occupancy. His findings have gained renewed attention with the recent description of the KcSa structure.

Acquisto del libro

Series of the Centro de Estudios Científicos: Pumps, Transporters, and Ion Channels, Francisco V. Sepúlveda, Francisco Bezanilla

Lingua
Pubblicato
2005
Rilegatura
(Copertina rigida),
Condizioni del libro
Danneggiato
Prezzo
19,54 €

Metodi di pagamento

Titolo
Series of the Centro de Estudios Científicos: Pumps, Transporters, and Ion Channels
Sottotitolo
Studies on Their Structure, Function, and Cell Biology
Lingua
Inglese
Editore
Springer
Pubblicato
2005
Formato
Copertina rigida
Pagine
182
ISBN10
0306486598
ISBN13
9780306486593
Serie
Descrizione
This compilation of articles features talks from the Centro de Estudios Cientificos (CECS) in Valdivia, celebrating the 60th birthdays of Ramon Latorre and Enrico Stefani. Ramon Latorre, a prominent figure in channel Biophysics, initially trained as a Biochemist but transitioned to biophysics under the mentorship of Guayo (Eduardo) Rojas during his Ph.D. at the Laboratorio de Fisiologia Celular in Montemar. His influential work at the N.I.H. with Gerald Ehrenstein and Harold Lecar marked a significant milestone in single ion channel Biophysics. This foundational research, conducted in planar bilayers, laid the groundwork for understanding voltage-dependent conductances through single channel studies, predating the later patch clamping techniques. Latorre was among the first to identify the significance of calcium-activated potassium channels and to investigate their properties in detail. He advanced the understanding of voltage and calcium modulation of open probability and conducted thorough studies on gating and its modulation by other ions. Additionally, he explored permeation and selectivity, producing seminal studies on water molecules within channels and barium occupancy. His findings have gained renewed attention with the recent description of the KcSa structure.