Wolfgang Arnold Libri

Otosclerosis is a disorder causing a hardening of the middle ear bones which leads to a progressive hearing loss. Internationally renowned experts met in Saas Fee (Switzerland) in 2004 to discuss otosclerosis and stapes surgery, and they have subsequently been invited by the editor to present their findings in this publication. From basic to clinical research, all relevant topics such as epidemiology, genetics, histopathology, molecular biology, and virus etiology are described. Also shown are the mechanics of the middle ear in model and in vivo, audiologic and imaging procedures, and surgical techniques including laser surgery. Further papers discuss advantages and disadvantages of stapes prosthesis, stapedectomy versus stapedotomy, and indications and contraindications of common therapies. Finally postsurgery complications and how to deal with them, short- and long term results, as well as the significance of stapes surgery in training and future developments are presented. This publication will keep the otorhinolaryngologist in clinic and practice up to date on current research and clinical development, but also pathologists, radiologists and virologists will find it inspiring reading.

The classic immunodeficient mutants nude, scid and rnu have an important function in experimental cancer they allow unique methods of investigation and provide data of clinical relevance. This volume presents the state of the art of research work based on the use of these immunodeficient animal models. One section is dedicated to the biological aspects and immunological properties of immunodeficient mutants. Another part includes articles on xenogenous transplantation of human tumors, focusing on the establishment of transplantable lines, growth characteristics and tumor markers. Special attention is given to new approaches in the fields of chemotherapy, radiation therapy and immunotherapy. Various contributors consider in vitro methods as alternative models. In addition to current data, this publication contains useful technical and methodological information and is therefore valuable not only for specialists but also for scientists entering the field of experimental cancer research.

Der Autor beleuchtet die düstere Geschichte von Kriegen, Völkermorden und wirtschaftlichen Krisen, die als Teil eines übergeordneten Plans verstanden werden. Diese Ereignisse, die das Leiden der Menschheit geprägt haben, sind nicht zufällig, sondern wurden strategisch und kaltblütig orchestriert. Auch die aktuellen Herausforderungen in Politik und Wirtschaft werden als Teil dieses geheimen Konzepts betrachtet, das nur von wenigen Eingeweihten erkannt wird.

Das Buch hinterfragt die Notwendigkeit eines kontinuierlichen Wachstums des Bruttosozialprodukts und beleuchtet die gesellschaftlichen und wirtschaftlichen Konsequenzen, die mit der ständigen Forderung nach mehr Konsum verbunden sind. Es thematisiert die Gefahren des Zusammenbruchs von Rentenversicherungen und Arbeitsplätzen, wenn das Wirtschaftswachstum stagniert. Zudem regt es an, über alternative Lebensweisen nachzudenken, die nicht auf immer mehr Arbeit und Konsum ausgerichtet sind, sondern Wege aus dem bestehenden Teufelskreis zu finden.