Gideon Blauer Libri

Frontmatter -- Preface -- Contents -- List Of Contributors -- Section I. General -- An Historical Survey of Porphyrins, their Related Spectra, and their Interpretation -- Routes to Functional Porphyrin Assemblies (Molecular Complexes, Covalent Redox Pairs, and Reactive Domains in Vesicles) -- Organism Dependent Pathways of Tetrapyrrole Biosynthesis -- Section II. Porphyrins And Metalloporphyrins -- Transient Absorption Spectra and Excited State Kinetics of Transition Metal Porphyrins -- Metal Complexes of Tetrapyrrole Ligands. XXXVII. Structure and Optical Spectra of Sandwich-Like Lanthanoid Porphyrins -- Excited State Electron Transfer of Carbonyl[mesotetra(p-tolyl) porphyrinato osmium(II)]Complexes. One and Two Electron Photoredox Processes -- Photophysical Properties of Hematoporphyrin and its Derivatives and their Use in Tumor Phototherapy -- Optical Properties of Ferriheme-Quinidine Complexes -- Resonance Raman Studies of Haemoglobin -- Optical Properties of Heme Bound to the Central Exon Fragment of Globins and to Corresponding Fragments in Cytochromes -- Heme Configuration in Cytochrome c -- Correlation between Near-Infrared, ESR Spectra and Oxidation- Reduction Potentials in Low-Spin Heme Proteins -- Circular Dichroism Contributions of Heme-Heme and Chlorophyll- Chlorophyll Interactions -- Optical Properties of Conjugated Proteins which Transport Haem, Porphyrins and Bilirubin -- Section III. Bile Pigments -- Light Absorption of Bilatrienes-abc and 2,3-Dihydrobilatrienes-abc -- Mechanism of Phototherapy of Neonatal Jaundice. Regiospecific Photoisomerization of Bilirubins -- Effects of Environment on Photophysical Processes of Bilirubin -- The Molecular Model of Phytochrome Deduced from Optical Probes -- Phytochrome, the Visual Pigment of Plants: Chromophore Structure and Chemistry of Photoconversion -- Recent Advances in the Photophysics and Photochemistry of Small, Large, and Native Oat Phytochromes -- Contents IX Time-Resolved Fluorescence Depolarisation of Phycocyanins in Different States of Aggregation -- The Influence of an External Electrical Charge on the Circular Dichroism of Chromopeptides from Phycocyanin -- Bilins and Bilin-Protein Linkages in Phycobili proteins: Structural and Spectroscopic Studies -- Structural Organization of Tetrapyrrole Pigments in Light- Harvesting Pigment-Protein Complexes -- The Crystal and Molecular Structure of C-Phycocyanin from Mastigocladus laminosus and its Implications for Function and Evolution -- Section IV. Chlorophylls -- Optical Spectra of Photosynthetic Reaction Centers. Theoretical and Experimental Aspects -- Circular Dichroism of Chlorophylls in Protein Complexes from Chloroplasts of Higher Plants: A Critical Assessment -- Optical Properties and Structure of Chlorophyll RC I -- Long-Wavelength Absorbing Forms of BacteriochlorophylIs. II. Structural Requirements for Formation in Triton X-100 Micelles and in Aqueous Methanol and Acetone -- Concluding Remarks -- Index of Contributors -- Subject Index -- Backmatter

This comprehensive work delves into various aspects of protein-ligand interactions, transport mechanisms, and the thermodynamics underlying these processes. It begins with an exploration of thermodynamics related to protein-ligand interactions and classifications of transport mechanisms through non-equilibrium thermodynamics. The investigation of membrane processes is further enhanced by chemical relaxation spectrometry and NMR studies of glycolysis in E. coli. The text then focuses on selected transport proteins, discussing serum albumin's role, intracellular binding proteins like ligandin and protein A, and the absence of heme-heme interactions in hemoglobin. It also examines multi-enzyme complexes, redox-transport modes, and energy transduction mechanisms in photophosphorylation. Subsequent sections cover proteins involved in mitochondrial calcium transport, the dynamics of proton transfer in bacteriorhodopsin, and the impact of cholesterol on mediated transport systems. The role of ion channels in excitable membranes is also highlighted. Metal transport by proteins is addressed, detailing ferritin's iron deposition, thermodynamic factors in iron binding to transferrin, and heme transport properties. A genetic defect in copper transport related to Wilson's disease is discussed. Finally, the physiological and pharmacological implications of protein transport are examined, including drug-binding properties of serum albumi