Analysis of NMR Chemical shifts in Peptide

and Protein Structure Determination - Guide for Using a Collection of Chemical Shift Data for Statistical Analysis and Its Application in Protein Structure Identification

Autori

• Liya Wang

Parametri

• 236 pagine
• 9 ore di lettura

• Biologia
• Scienze Naturali

Maggiori informazioni sul libro

The book delves into the complexities of analyzing NMR chemical shifts in biomolecules, focusing on the concept of "congruence" for data sets that allow for direct statistical analysis after necessary adjustments. It identifies congruence issues at three levels: protein, residue, and refined residue, highlighting the need for corrections such as subtracting random coil shifts and considering neighboring residue effects. Through newly proposed robust statistical models, the book addresses these challenges, enhancing the understanding and application of chemical shift data in biochemistry.

Lingua: Inglese

Pubblicato: 2012

(In brossura)