Profiling of Quinolone-Resistant Plasmids from Pyogenic Skin Infection

Molecular Diagnosis of Plasmid Mediaated Quinolone Resistance

Autori

• Shami Chakrabarti

Parametri

• 64 pagine
• 3 ore di lettura

• Biologia
• Scienze Naturali

Maggiori informazioni sul libro

The study investigates antibiotic susceptibility in 21 patients with pyogenic skin infections, revealing that only four samples were quinolone-susceptible. Notably, some quinolone-resistant strains were also methicillin-resistant, with a predominance of gram-positive isolates. Plasmid isolation was successful in 8 out of 17 clinical isolates, including a unique quinolone-susceptible but methicillin-resistant strain. These plasmids displayed distinct patterns when digested with specific enzymes, and transformation experiments showed that six samples conferred quinolone resistance to sensitive E. coli cells.

Lingua: Inglese

Pubblicato: 2013

(In brossura)