Measuring Dynamic Network Interactions

that Control Pituitary Gene Expression

Autori

• Ignacio Demarco

Parametri

• 172 pagine
• 7 ore di lettura

• Genetica

Maggiori informazioni sul libro

The book explores the role of the homeodomain protein Pit-1 in the development of anterior pituitary cells, highlighting its interactions with transcription factors and coregulatory proteins. It presents new findings from biochemical studies and live-cell imaging that reveal how proteins move and form complexes within the nucleus. The research indicates that the assembly of these proteins is influenced by their chromatin-binding activities, suggesting a mechanism for regulating gene expression. Additionally, it connects the mislocalization of transcriptional complexes to disease processes.

Lingua: Inglese

Pubblicato: 2012

(In brossura)