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The book explores the intricate process of cardiac aging, highlighting the cellular and molecular changes that result in various aging phenotypes. It discusses multiple theories, including evolutionary and free radical theories, suggesting that these concepts are interconnected rather than mutually exclusive. The text emphasizes the role of genetic and epigenetic factors in cardiovascular aging, supported by animal studies demonstrating significant lifespan alterations through gene engineering and dietary changes, such as caloric restriction, illustrating the complex interplay of genetics and environment.
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Aging and the Heart, José Marín-García
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- 2007
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