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Focusing on the mechanisms behind chronic obstructive pulmonary disease (COPD), this book explores the role of cellular senescence and DNA damage in the disease's progression. It highlights how cigarette smoking leads to tissue destruction and inflammation, contributing to lung regression. The text delves into the cellular processes involved in growth arrest and the activation of DNA repair mechanisms, emphasizing the connection between lung health and the viability of resident and progenitor cells. This work presents a compelling perspective on COPD as a condition of premature lung aging.
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Senescence, DNA damage and repair in COPD, Manish Kumar
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- Pubblicato
- 2015
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