Siddhartha Mukherjee Ordine dei libri (cronologico)

Als im späten 16. Jahrhundert der englische Universalgelehrte Robert Hooke und der holländische Tuchhändler Antonie van Leeuwenhoek durch ihre handgefertigten Mikroskope blickten, sahen sie etwas, was der Biologie und der Medizin ein radikal neues Konzept hinzufügte und beide Wissenschaften für immer veränderte: Komplexe Organismen bestehen aus winzigen, in sich geschlossenen und sich selbst regulierenden Einheiten. Unsere Organe, unsere Physiologie, unser Selbst - Herz, Blut, Gehirn - sind aus diesen kleinen Teilen aufgebaut: den Zellen. Sie ermöglichen all unsere komplexen Körperfunktionen: Immunabwehr, Fortpflanzung, Empfindungsvermögen, Kognition und Erneuerung. Die Schattenseite ist die ungemeine Zerstörungskraft dysfunktionaler Zellen, die einen Körper seiner Lebensfähigkeit berauben können. Mukherjee erzählt vom enormen Potenzial unseres vertieften Verständnisses der Zellphysiologie und -pathologie. Es hat eine Revolution in Biologie und Medizin ausgelöst, transformative Medikamente hervorgebracht und Menschen verändert.

From the prize-winning author of The Emperor of All Maladies, The Song of the Cell tells the vivid, thrilling and suspenseful story of the fundamental unit of life. Both panoramic and intimate, this is Siddhartha Mukherjee's most spectacular book yet. In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that alters both biology and medicine forever. It is the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves, are built from these compartments. Hooke christens them 'cells'. The discovery of cells announced the birth of a new kind of medicine. A hip fracture, a cardiac arrest, Alzheimer's, AIDS, lung cancer - all could be re-conceived as the results of cells, or a cellular ecosystem, functioning abnormally. And all could be treated by therapeutic manipulations of cells. This revolution in cell biology is still in progress: it represents one of the most significant advances in science and medicine. Rich with stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer's exploration of what it means to be human.

'A brilliant, authoritative, surprising, captivating introduction to human genetics. You'll be spellbound' Brian Cox This is a story about you. It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species - births, deaths, disease, war, famine, migration and a lot of sex. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about human history, and what history can now tell us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be. *** 'A thoroughly entertaining history of Homo sapiens and its DNA in a manner that displays popular science writing at its best' Observer 'Magisterial, informative and delightful' Peter Frankopan 'An extraordinary adventure...From the Neanderthals to the Vikings, from the Queen of Sheba to Richard III, Rutherford goes in search of our ancestors, tracing the genetic clues deep into the past' Alice Roberts

Spanning the globe and several centuries, this is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function. It is also an intimate history - the story of the author's own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives.

One of the world's premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine--and how understanding these principles can empower everyone.

Selected as One of the Best Books of the 21st Century by The New York Times Winner of the Pulitzer Prize, adapted as a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.